METHODS FOR PREPARING HYDROXY COMPOUNDS AND INTERMEDIATES
A method for preparing an unprotected hydroxy compound from a protected hydroxy compound of the general formula I in which R1 is the non-hydroxy moiety of the protected hydroxy compound; R2, R3, R4 and R5 which may be the same or different are hydrogen, C1-4 alkyl or aryl; and R6, R7 and R8 which ma...
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| creator | MAGNUSSON, HANS GORAN JANSSON, KARL MIKAEL HANSEN KOLLEGIUM B 107 |
| description | A method for preparing an unprotected hydroxy compound from a protected hydroxy compound of the general formula I in which R1 is the non-hydroxy moiety of the protected hydroxy compound; R2, R3, R4 and R5 which may be the same or different are hydrogen, C1-4 alkyl or aryl; and R6, R7 and R8 which may be same or different are C1-4 alkyl, optionally substituted phenyl or a carrier in which the compound of formula I is reacted with a Lewis acid followed by reaction with water forming a hydroxy compound of the general formula II R1-OH II; A method for preparing a compound of the general formula III R1-O-A III in which R1 is the non-hydroxy moiety of a hydroxy compound; and A is an acyl group; A compound of the general formula IV R1-O-X IV in which R1 is the non-hydroxy moiety of a hydroxy compound; and X is a residue of a Lewis acid; A method according to claim 4 in which R1 is the non-hydroxy moiety of a hydroxy-containing amino acid forming part of a peptide, and one of R6, R7 and R8 is a carrier; and A compound of the general formula Ia wherein R1 is a carbohydrate moiety containing two or more sugar units or a derivative thereof. |
| format | Patent |
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R2, R3, R4 and R5 which may be the same or different are hydrogen, C1-4 alkyl or aryl; and R6, R7 and R8 which may be same or different are C1-4 alkyl, optionally substituted phenyl or a carrier in which the compound of formula I is reacted with a Lewis acid followed by reaction with water forming a hydroxy compound of the general formula II R1-OH II; A method for preparing a compound of the general formula III R1-O-A III in which R1 is the non-hydroxy moiety of a hydroxy compound; and A is an acyl group; A compound of the general formula IV R1-O-X IV in which R1 is the non-hydroxy moiety of a hydroxy compound; and X is a residue of a Lewis acid; A method according to claim 4 in which R1 is the non-hydroxy moiety of a hydroxy-containing amino acid forming part of a peptide, and one of R6, R7 and R8 is a carrier; and A compound of the general formula Ia wherein R1 is a carbohydrate moiety containing two or more sugar units or a derivative thereof.</description><edition>4</edition><language>eng</language><subject>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM ; 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R2, R3, R4 and R5 which may be the same or different are hydrogen, C1-4 alkyl or aryl; and R6, R7 and R8 which may be same or different are C1-4 alkyl, optionally substituted phenyl or a carrier in which the compound of formula I is reacted with a Lewis acid followed by reaction with water forming a hydroxy compound of the general formula II R1-OH II; A method for preparing a compound of the general formula III R1-O-A III in which R1 is the non-hydroxy moiety of a hydroxy compound; and A is an acyl group; A compound of the general formula IV R1-O-X IV in which R1 is the non-hydroxy moiety of a hydroxy compound; and X is a residue of a Lewis acid; A method according to claim 4 in which R1 is the non-hydroxy moiety of a hydroxy-containing amino acid forming part of a peptide, and one of R6, R7 and R8 is a carrier; and A compound of the general formula Ia wherein R1 is a carbohydrate moiety containing two or more sugar units or a derivative thereof.</description><subject>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM</subject><subject>CHEMISTRY</subject><subject>DERIVATIVES THEREOF</subject><subject>METALLURGY</subject><subject>NUCLEIC ACIDS</subject><subject>NUCLEOSIDES</subject><subject>NUCLEOTIDES</subject><subject>ORGANIC CHEMISTRY</subject><subject>SUGARS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1987</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZLD0dQ3x8HcJVnDzD1IICHINcAzy9HNX8Ih0CfKPiFRw9vcN8A_1A8o7-rkoePqFuAb5urp4Ooa4BvMwsKYl5hSn8kJpbgYFN9cQZw_d1IL8-NTigsTk1LzUknjXAAMjY0tDSxNHY2MilAAAZQMotw</recordid><startdate>19871111</startdate><enddate>19871111</enddate><creator>MAGNUSSON, HANS GORAN</creator><creator>JANSSON, KARL MIKAEL HANSEN KOLLEGIUM B 107</creator><scope>EVB</scope></search><sort><creationdate>19871111</creationdate><title>METHODS FOR PREPARING HYDROXY COMPOUNDS AND INTERMEDIATES</title><author>MAGNUSSON, HANS GORAN ; JANSSON, KARL MIKAEL HANSEN KOLLEGIUM B 107</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_EP0239194A33</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng</language><creationdate>1987</creationdate><topic>ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM</topic><topic>CHEMISTRY</topic><topic>DERIVATIVES THEREOF</topic><topic>METALLURGY</topic><topic>NUCLEIC ACIDS</topic><topic>NUCLEOSIDES</topic><topic>NUCLEOTIDES</topic><topic>ORGANIC CHEMISTRY</topic><topic>SUGARS</topic><toplevel>online_resources</toplevel><creatorcontrib>MAGNUSSON, HANS GORAN</creatorcontrib><creatorcontrib>JANSSON, KARL MIKAEL HANSEN KOLLEGIUM B 107</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>MAGNUSSON, HANS GORAN</au><au>JANSSON, KARL MIKAEL HANSEN KOLLEGIUM B 107</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>METHODS FOR PREPARING HYDROXY COMPOUNDS AND INTERMEDIATES</title><date>1987-11-11</date><risdate>1987</risdate><abstract>A method for preparing an unprotected hydroxy compound from a protected hydroxy compound of the general formula I in which R1 is the non-hydroxy moiety of the protected hydroxy compound; R2, R3, R4 and R5 which may be the same or different are hydrogen, C1-4 alkyl or aryl; and R6, R7 and R8 which may be same or different are C1-4 alkyl, optionally substituted phenyl or a carrier in which the compound of formula I is reacted with a Lewis acid followed by reaction with water forming a hydroxy compound of the general formula II R1-OH II; A method for preparing a compound of the general formula III R1-O-A III in which R1 is the non-hydroxy moiety of a hydroxy compound; and A is an acyl group; A compound of the general formula IV R1-O-X IV in which R1 is the non-hydroxy moiety of a hydroxy compound; and X is a residue of a Lewis acid; A method according to claim 4 in which R1 is the non-hydroxy moiety of a hydroxy-containing amino acid forming part of a peptide, and one of R6, R7 and R8 is a carrier; and A compound of the general formula Ia wherein R1 is a carbohydrate moiety containing two or more sugar units or a derivative thereof.</abstract><edition>4</edition><oa>free_for_read</oa></addata></record> |
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| subjects | ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY DERIVATIVES THEREOF METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY SUGARS |
| title | METHODS FOR PREPARING HYDROXY COMPOUNDS AND INTERMEDIATES |
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