3-(2-AMINOETHYL)INDOLE AND -INDOLINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

A compound of formula (1) or a pharmaceutically acceptable salt thereof:wherein:R, is hydrogen, C1-6 alkyl, C1-6 alkoxy or halogen;R2 and R3 are both hydrogen or together represent a bond;R4 is selected from C1-6 alkyl, phenyl, phenyl-C1-4 alkyl, CORe where R8 is hydroxy, C1-6 alkoxy or NR9R10 where...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	THIELKE, DIETRICH, HOELTJE, DAGMAR
Format:	Patent
Sprache:	eng
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	A compound of formula (1) or a pharmaceutically acceptable salt thereof:wherein:R, is hydrogen, C1-6 alkyl, C1-6 alkoxy or halogen;R2 and R3 are both hydrogen or together represent a bond;R4 is selected from C1-6 alkyl, phenyl, phenyl-C1-4 alkyl, CORe where R8 is hydroxy, C1-6 alkoxy or NR9R10 where R9 and R10 are independently hydrogen or C1-4 alkyl and CH2OR11 where R11 is hydrogen, C1-4 alkyl or C1-4 alkanoyl;R6 is hydrogen, C1-6 alkyl or phenyl C1-4 alkyl;R6 is phenyl C1-7 alkyl in which the phenyl moiety is optionally substituted by one or two of halogen, ortho-nitro. meta-or para-methoxy, methyl or NR12R13 wherein R12 and R13 are independently hydrogen or C1-6 alkyl or R12 and R13 together are C2-6 polymethylene or the phenyl moiety is 3,4- disubstituted by methylenedioxy or ethylenedioxy; andR7 is hydrogen or C1-4 alkyl, processes for its preparation and its use as a pharmaceutical.