AROMATIC HYDROXY- OR THIOL DERIVATIVES OF CARBONIC-ACID ESTERS AS LIPASE SUBSTRATES

The present invention provides a lipase substrate of the general formula: wherein A is an alkylene or alkenylene radical containing up to 16 carbon atoms, R and R1, which can be the same or different, each signify an alkyl, alkenyl or acyl radical containing up to 20 carbon atoms or an optionally al...

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Hauptverfasser: NEUMANN, ULRICH NAT, BATZ, HANS-GEORG NAT, JUNIUS, MARTINA NAT
Format: Patent
Sprache:eng ; ger
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Zusammenfassung:The present invention provides a lipase substrate of the general formula: wherein A is an alkylene or alkenylene radical containing up to 16 carbon atoms, R and R1, which can be the same or different, each signify an alkyl, alkenyl or acyl radical containing up to 20 carbon atoms or an optionally alkyl-substituted aryl or aralkyl radical containing up to 8 carbon atoms in the alkyl moiety and wherein one of R and R1 can also be a hydrogen atom, X is the residue of an aromatic hydroxy or thiol compound, and each Y and Z, independently from each other, is -S- or -O-, Z also -CH2-. The present invention also provides a process and a reagent for the optical determination of lipase.