7-HYDROXYGUANINE COMPOUNDS, PROCESS FOR PREPARING SAID COMPOUNDS, THEIR USE AND ANTI-TUMOR AGENT CONTAINING THE SAME

@ Novel 7-hydroxyguanine compounds of the formula:wherein R is hydrogen atom, tetrahydropyranyl group or tetrahydrofuryl group, and R2 is hydrogen atom, tetrahydropyranyl group ortetrahydrofuryl group, provided that when R, is hydrogen atom, R2 is tetrahydropyranyl group or tetrahydrofuryl group, an...

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Hauptverfasser: ISHII, KIYOTO, WATANABE, KIYOSHI, KAWAHARADA, HAJIME
Format: Patent
Sprache:eng
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Zusammenfassung:@ Novel 7-hydroxyguanine compounds of the formula:wherein R is hydrogen atom, tetrahydropyranyl group or tetrahydrofuryl group, and R2 is hydrogen atom, tetrahydropyranyl group ortetrahydrofuryl group, provided that when R, is hydrogen atom, R2 is tetrahydropyranyl group or tetrahydrofuryl group, and a salt thereof, which have excellent anti-tumor activity, process for preparing the compounds, and anti-tumor agent containing said compound as an active ingredient. The 7-hydroxy compounds can be used forthe preparation of a medicament for the prophylaxis and treatment of tumors.