OXIDATION RESISTANT IL-2 MUTEINS AND THEIR PRODUCTION, FORMULATIONS CONTAINING SUCH MUTEINS, AND DNA SEQUENCES AND EXPRESSION VECTORS CODING FOR SUCH MUTEINS AND CORRESPONDING TRANSFORMED HOST CELLS

A biologically active reference (e.g. human) IL-2 (interleukin-2) protein is protected against oxidation by a method involving substituting a conservative amino acid for each methionine residue susceptible to chloramine T or peroxide oxidation and wherein additional, non-susceptible methionine resid...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	KOTHS, KIRSTON EDWARD, HALENBECK, ROBERT FORGAN, INNIS, MICHAEL ALLAN
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF COMPOUNDS OF UNKNOWN CONSTITUTION CULTURE MEDIA DERIVATIVES THEREOF ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PEPTIDES PROCESSES USING MICROORGANISMS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS SUGARS VINEGAR WINE
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	A biologically active reference (e.g. human) IL-2 (interleukin-2) protein is protected against oxidation by a method involving substituting a conservative amino acid for each methionine residue susceptible to chloramine T or peroxide oxidation and wherein additional, non-susceptible methionine residues are not so substituted.