Compounds having antihyperlipemic activity, processes for the preparation thereof and pharmaceutical compositions containing them

Compounds having antihyperlipemic activity, processes for the preparation thereof and pharmaceutical compositions containing them

Novel bis(hydroxy-2-ethylthio)-1, 10-decane esters with N-etaroyl aminoacids are described. The compounds of the invention have valuable biological characteristics, such as high adsorption degree by oral route, sustained hypolipidemic and antilipolytic activities, without rebound effect, as well as...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: SPINELLI, SILVANO, TOFANETTI, ODOARDO, CASCIARRI, IGINO
Format: Patent
Sprache:eng ; fre ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:Novel bis(hydroxy-2-ethylthio)-1, 10-decane esters with N-etaroyl aminoacids are described. The compounds of the invention have valuable biological characteristics, such as high adsorption degree by oral route, sustained hypolipidemic and antilipolytic activities, without rebound effect, as well as poor side-effects.