MINACTIVIN

Minactivin, a protein inactivator of urokinase-type plasminogen activator, has been shown to be a natural inactivator of this plasminogen activator which is associated with invasive tumours, and is therefore indicated as a crucial element in the body's normal defense against tumour invasion and...

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Bibliographische Detailangaben
Hauptverfasser: GOLDER, JEFFREY, PHILIP, STEPHENS, ROSS, WENTWORTH, ANTALIS, TONI, MARIE, GOSS, NEIL, HOWARD
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:Minactivin, a protein inactivator of urokinase-type plasminogen activator, has been shown to be a natural inactivator of this plasminogen activator which is associated with invasive tumours, and is therefore indicated as a crucial element in the body's normal defense against tumour invasion and metastasis. It may be produced by the cultivation of miniactivin-producing cells in vitro, and recovery of the cell culture supernatant. By controlling the culture conditions, the protein miniactivin may be produced in a partially purified form which may be used for diagnosis and treatment of tumours.