OMEGA-(2',4'-DIHALOBIPHENYLYL)OXO ALKANOIC ACIDS AND PROCESS FOR THEIR PREPARATION

New Omega-(2 min , 4 min -dihalobiphenylyl)-oxo alkanoic acids are prepared by reacting a 2,4-dihalobiphenyl with the anhydride of methylsuccinic or glutaric acid under conditions of Friedel-Crafts acylation. The new compounds show remarkable antiinflammatory properties with unexpectedly prolonged d...

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Hauptverfasser: GRIMOVA, JAROSLAVA, CSC, BRUNOVA, BOHUMILA, CSC, KUCHAR, MIROSLAV, CSC, MATUROVA, EVA
Format: Patent
Sprache:eng
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Zusammenfassung:New Omega-(2 min , 4 min -dihalobiphenylyl)-oxo alkanoic acids are prepared by reacting a 2,4-dihalobiphenyl with the anhydride of methylsuccinic or glutaric acid under conditions of Friedel-Crafts acylation. The new compounds show remarkable antiinflammatory properties with unexpectedly prolonged duration of the effect.