METHOD FOR THE DETERMINATION OF FREE SUBSTANCES IN BIOLOGICAL FLUIDS

In the determination of free substances, in particular free hormones such as the thyroid hormones T3 and T4, in biological fluids, a third component is added to the biological fluid in addition to the usual components tracer and antibody, which lessens the rebinding of the tracer to the binding prot...

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1. Verfasser: BIENHAUS, GERHARD
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Sprache:eng ; ger
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Zusammenfassung:In the determination of free substances, in particular free hormones such as the thyroid hormones T3 and T4, in biological fluids, a third component is added to the biological fluid in addition to the usual components tracer and antibody, which lessens the rebinding of the tracer to the binding proteins present in the sample. Suitable third components of this type are in particular various thyroid hormone analogues and highly concentrated solutions of ionisable salts.