PROCESS FOR THE PREPARATION OF CEPHALOSPORINS

PROCESS FOR THE PREPARATION OF CEPHALOSPORINS

A process for the preparation of a cephalosporin of the formula in which R1 is an aliphatic or cycloaliphatic radical with up to 6 carbon atoms, and A is a pyridinium radical or a radical of the formula comprising reacting an acid of the formula with methanesulphonyl chloride to form an anhydride of...

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Bibliographische Detailangaben
Hauptverfasser: KINAST, GUNTHER, ANGERBAUER, ROLF
Format: Patent
Sprache:eng ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:A process for the preparation of a cephalosporin of the formula in which R1 is an aliphatic or cycloaliphatic radical with up to 6 carbon atoms, and A is a pyridinium radical or a radical of the formula comprising reacting an acid of the formula with methanesulphonyl chloride to form an anhydride of the formula and reacting the anhydride with a 7-aminocephalosporanate of the formula The reaction proceeds smoothly and in high yield.