HEPATITIS B VACCINE AND METHOD FOR ITS PREPARATION

HEPATITIS B VACCINE AND METHOD FOR ITS PREPARATION

Lyophilized preparation of hepatitis B vaccine, which comprises an inactivated, purified hepatitis B virus surface antigen adsorbed on an aluminium gel and a stabilizer in the lyophilized state, which is prepared by adding an aluminium gel and a stabilizer to an inactivated, purified hepatitis B vir...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: ISHIHARA, YOSHIMITSU, OHTOMO, NOBUYA, KAWAHARA, TETSUO, MIZUNO, KYOSUKE
Format: Patent
Sprache:eng
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:Lyophilized preparation of hepatitis B vaccine, which comprises an inactivated, purified hepatitis B virus surface antigen adsorbed on an aluminium gel and a stabilizer in the lyophilized state, which is prepared by adding an aluminium gel and a stabilizer to an inactivated, purified hepatitis B virus surface antigen and lyophilizing the mixture. Said lyophilized preparation being able to be stably kept for a long period of time without loosing its antigen titer and being useful for the prophylaxis of a hepatitis B virus infection.