PROCESS FOR THE PREPARATION OF E-ISOMERS OF 1-CYCLOHEXYL-2-(1,2,4-TRIAZOL-1-YL)-1-PENTEN-3-ONES

PROCESS FOR THE PREPARATION OF E-ISOMERS OF 1-CYCLOHEXYL-2-(1,2,4-TRIAZOL-1-YL)-1-PENTEN-3-ONES

The known E-isomers of compounds of the formula (I) in which X and Y independently of each other represent hydrogen or halogen, are obtained according to a new process, in which triazolylketones of the formula (I) in which X and Y have the above mentioned meaning, are reacted with an excess of cyclo...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: REISER, WOLF, FEYEN, PETER, RAULEDER, GEBHARD
Format: Patent
Sprache:eng ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The known E-isomers of compounds of the formula (I) in which X and Y independently of each other represent hydrogen or halogen, are obtained according to a new process, in which triazolylketones of the formula (I) in which X and Y have the above mentioned meaning, are reacted with an excess of cyclohexanecarbaldehyde in the presence of a non-polar organic diluent and in the presence of a catalyst mixture of organic acids and secondary amines in a molar ratio of 1:0.5 to 1:1 at temperatures between 40 DEG and 100 DEG C. by continuously removing the water formed and subsequently working up in the manner that is described in the specification.