Derivatives of 9-(2-hydroxyethoxymethyl)guanine

Compounds of the general formula(wherein X represents an oxygen or sulphur atomR' represents a hydroxy or amino groupR2 represents a hydrogen atom or a group of formula -CN2OR3aand R3 and R3a which may be the same or different, each represents an amino acid acyl radical) and physiologically acc...

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Bibliographische Detailangaben
Hauptverfasser:	DE CLERCQ, ERIK D. A. P, BUSSON, ROGER H. C, VANDER HAEGHEN, HUBERT J. H. E
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Compounds of the general formula(wherein X represents an oxygen or sulphur atomR' represents a hydroxy or amino groupR2 represents a hydrogen atom or a group of formula -CN2OR3aand R3 and R3a which may be the same or different, each represents an amino acid acyl radical) and physiologically acceptable salts thereof are useful for the treatment if viral infections and have been found to have a surprisingly high water-solubility which renders them of value in the formulation of aqueous pharmaceutical preparations. Processes for preparing the compounds are described.