INCLUSION COMPLEXES OF N-(1-PHENYLETHYL)-3,3-DIPHENYLPROPYLAMINE RESPECTIVELY THE HYDROCHLORIDE THEREOF WITH CYCLODEXTRIN, A PROCESS FOR THE PREPARATION OF THESE INCLUSION COMPLEXES AS WELL AS PHARMACEUTICAL PREPARATIONS CONTAINING THESE INCLUSION COMPLEXES

INCLUSION COMPLEXES OF N-(1-PHENYLETHYL)-3,3-DIPHENYLPROPYLAMINE RESPECTIVELY THE HYDROCHLORIDE THEREOF WITH CYCLODEXTRIN, A PROCESS FOR THE PREPARATION OF THESE INCLUSION COMPLEXES AS WELL AS PHARMACEUTICAL PREPARATIONS CONTAINING THESE INCLUSION COMPLEXES

PCT No. PCT/HU82/00024 Sec. 371 Date Dec. 22, 1982 Sec. 102(e) Date Dec. 22, 1982 PCT Filed May 12, 1982 PCT Pub. No. WO82/04052 PCT Pub. Date Nov. 25, 1982.An inclusion complex is disclosed of N-(1-phenylethyl)-3, 3-diphenyl-propylamine or its hydrochloride complexed with a cyclodextrin as well as...

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Hauptverfasser: KISS, PAL, STADLER, AGNES, TURCSAN, ISTVAN, VIRAG, SANDOR, SZEJTLI, JOZSEF, VIKMON, MARIA, KORBONITS, DEZSO
Format: Patent
Sprache:eng ; ger
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CHEMISTRY
COMPOSITIONS BASED THEREON
DERIVATIVES THEREOF
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC MACROMOLECULAR COMPOUNDS
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PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:PCT No. PCT/HU82/00024 Sec. 371 Date Dec. 22, 1982 Sec. 102(e) Date Dec. 22, 1982 PCT Filed May 12, 1982 PCT Pub. No. WO82/04052 PCT Pub. Date Nov. 25, 1982.An inclusion complex is disclosed of N-(1-phenylethyl)-3, 3-diphenyl-propylamine or its hydrochloride complexed with a cyclodextrin as well as a process for the preparation thereof and pharmaceutical compositions containing same. The new inclusion complexes have coronary dilatory activity and have greater water soluble than simple N-(1-phenylethyl)-3, 3-diphenyl-propyl amine or the hydrochloride thereof.