2-PIPERAZINO-PYRIMIDINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, MEDICAMENTS CONTAINING THEM AND THEIR USE AS INTERMEDIATES IN THE MANUFACTURE OF MEDICAMENTS

2-PIPERAZINO-PYRIMIDINE DERIVATIVES, PROCESSES FOR THEIR PREPARATION, MEDICAMENTS CONTAINING THEM AND THEIR USE AS INTERMEDIATES IN THE MANUFACTURE OF MEDICAMENTS

Compounds are disclosed as useful as drugs or as intermediates for the manufacture of drugs, the compounds having the formula: (I) in which X is hydrogen, chlorine, alkyl, alkoxy or alkylthio having 1 to 3 carbon atoms, R2 is hydrogen or alkyl having 1 to 3 carbon atoms, Y2 is chlorine and Y1 is chl...

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Bibliographische Detailangaben
Hauptverfasser: GUEREMY, CLAUDE GEORGES ALEXANDRE, LE FUR, GERARD ROGER, AUDIAU, FRANCOIS
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Compounds are disclosed as useful as drugs or as intermediates for the manufacture of drugs, the compounds having the formula: (I) in which X is hydrogen, chlorine, alkyl, alkoxy or alkylthio having 1 to 3 carbon atoms, R2 is hydrogen or alkyl having 1 to 3 carbon atoms, Y2 is chlorine and Y1 is chlorine or in which R1 is hydrogen, straight or branched chain alkyl having 1 to 7 carbon atoms, cycloalkyl having 3 to 7 carbon atoms or cycloalkylalkyl having 4 to 8 carbon atoms, or Y2 and Y1 are both OH. Also disclosed are methods for preparation of the compounds.