Levonantradol and N-methyllevonantradol formulations

A pharmaceutical composition comprising an aqueous micellar solution of, as the active ingredient, (a) levonantradol or (b) N-methyllevonantradol, or a pharmaceutically acceptable acid addition salt of (a) or (b), and (c) at least a critical micelle concentration of a nonionic amphiphile. Also cover...

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Bibliographische Detailangaben
Hauptverfasser: AGUIAR, ARMANDO JOSEPH, RASADI, BIJAN
Format: Patent
Sprache:eng ; fre ; ger
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Zusammenfassung:A pharmaceutical composition comprising an aqueous micellar solution of, as the active ingredient, (a) levonantradol or (b) N-methyllevonantradol, or a pharmaceutically acceptable acid addition salt of (a) or (b), and (c) at least a critical micelle concentration of a nonionic amphiphile. Also covered are pharmaceutically acceptable lyophile compositions prepared by the lyophilization of the aqueous micellar solutions. Levonantradol and N-methyllevonantradol are analgetic and anti-emetic agents.