Method of binding a biologically active material, e.g. a protein to a carrier containing hydroxyl groups

Methods of binding a biologically active material containing hydroxyl groups are disclosed in which an isocyanate compound is bound to the carrier and the protein is bound to the so bound isocyanate compound. The binding of the isocyanate compound to the carrier is achieved with the use of an agent,...

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Bibliographische Detailangaben
Hauptverfasser:	KRISAM, GERD GUSTAV, GOLLA, RUTH SIBYLLE, LEHMANN, HANS-DIETER
Format:	Patent
Sprache:	eng ; fre ; ger
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS BASED THEREON COMPOSITIONS THEREOF CULTURE MEDIA DEVICES FOR INTRODUCING MEDIA INTO, OR ONTO, THE BODY DEVICES FOR PRODUCING OR ENDING SLEEP OR STUPOR DEVICES FOR TRANSDUCING BODY MEDIA OR FOR TAKING MEDIA FROMTHE BODY ENZYMOLOGY HUMAN NECESSITIES HYGIENE MACROMOLECULAR COMPOUNDS OBTAINED OTHERWISE THAN BY REACTIONSONLY INVOLVING UNSATURATED CARBON-TO-CARBON BONDS MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC MACROMOLECULAR COMPOUNDS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS THEIR PREPARATION OR CHEMICAL WORKING-UP VINEGAR WINE
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Beschreibung
Zusammenfassung:	Methods of binding a biologically active material containing hydroxyl groups are disclosed in which an isocyanate compound is bound to the carrier and the protein is bound to the so bound isocyanate compound. The binding of the isocyanate compound to the carrier is achieved with the use of an agent, having the capability of catalytically forming urethane. Examples of such agents may be non-toxic agents on the basis of titanium, for example, orthotitanium acid esters, and preferably tetrabutyltitanate.