PROCESS FOR PREPARING 3-AMINO-1-HYDROXYPROPANE-1,1-DIPHOSPHONIC ACID

PROCESS FOR PREPARING 3-AMINO-1-HYDROXYPROPANE-1,1-DIPHOSPHONIC ACID

A process for the preparation of 3-amino-1-hydroxypropane-1,1-diphosphonic acid having the formula: wherein R1 and R2 are selected from the group consisting of hydrogen and lower alkyl, consisting essentially of the steps of reacting a beta -alanine compound selected from the group consisting of bet...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: BLUM, HELMUT, WORMS, KARL-HEINZ
Format: Patent
Sprache:eng ; ger
Schlagworte:
ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM
CHEMISTRY
METALLURGY
ORGANIC CHEMISTRY
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:A process for the preparation of 3-amino-1-hydroxypropane-1,1-diphosphonic acid having the formula: wherein R1 and R2 are selected from the group consisting of hydrogen and lower alkyl, consisting essentially of the steps of reacting a beta -alanine compound selected from the group consisting of beta -alanine and lower alkylated beta -alanine with a phosphonating reactant selected from the group consisting of: (1) a mixture of phosphorous acid and PCl5, and (2) a mixture of phosphorous acid, PCl3 and Cl2, hydrolyzing the reaction mixture, and recovering said 3-amino-1-hydroxypropane-1,1-diphosphonic acid.