PROCESS FOR PREPARING 4-METHYL-5-((2-AMINOETHYL)-THIOMETHYL)-IMIDAZOLE-DIHYDRO CHLORIDE

PROCESS FOR PREPARING 4-METHYL-5-((2-AMINOETHYL)-THIOMETHYL)-IMIDAZOLE-DIHYDRO CHLORIDE

4-Methyl-5-[(2-aminoethyl)-thiomethyl]-imidazole dihydrochloride is prepared in a single-step process by thiomethylating 4-methylimidazole. The product is an intermediate for other imidazole derivatives, especially the drug cimetidine.

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Bibliographische Detailangaben
1. Verfasser: HALBRITTER, KLAUS
Format: Patent
Sprache:eng ; ger
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:4-Methyl-5-[(2-aminoethyl)-thiomethyl]-imidazole dihydrochloride is prepared in a single-step process by thiomethylating 4-methylimidazole. The product is an intermediate for other imidazole derivatives, especially the drug cimetidine.