ANTIBIOTICS AND PHARMACEUTICAL COMPOSITIONS CONTAINING THEM

The invention relates to new antibiotics produced by a new species of Nocardia designated Nocardia argentinensis Huang sp. nov. ATCC 31306. Specific novel antibiotics are designated Compounds 47,444, 47,985 and 48,039, the first of which has been isolated in pure form as an amorphous solid character...

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Bibliographische Detailangaben
Hauptverfasser:	MOPPETT, CHARLES EDWARD, SHIBAKAWA, RIICHIRO, CULLEN, WALTER PATRICK, TONE, JUNSUKE, JEFFERSON, MARK TILDEN, CELMER, WALTER DANIEL, HUANG, LIANG HSIUNG
Format:	Patent
Sprache:	eng
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOUNDS OF UNKNOWN CONSTITUTION ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROCESSES USING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention relates to new antibiotics produced by a new species of Nocardia designated Nocardia argentinensis Huang sp. nov. ATCC 31306. Specific novel antibiotics are designated Compounds 47,444, 47,985 and 48,039, the first of which has been isolated in pure form as an amorphous solid characterised by solubility, elemental analysis, optical rotation, and ultraviolet and infra-red absorption spectra. Antibacterial activity, particularly against normally resistant strains of Staphylococcus aureus, is disclosed.