Novel pyrroles derivatives as pharmaceutical agents

Novel pyrrazole derivative compounds and their use as pharmaceutical agents, in particular their use as TGF-beta signal transduction inhibitors. The disclosed invention relates to compounds of the structure (I) wherein (I) is a four, five, or six membered saturated ring and X is C, O or S

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Bibliographische Detailangaben
Hauptverfasser: BEIGHT DOUGLAS WADE, GODFREY ALEXANDER GLENN, MCMILLEN WILLIAM THOMAS, MORT NICOLAS ANTHONY, YINGLING JONATHAN MICHAEL, JUNKAI LIAO, SAWYER JASON SCOTT, GOODSON THEODORE JR, SMITH EDWARD C R, LI HONG-YU, CIAPETTI PAOLA, HERRON DAVID KENT, MILLER SHAWN CHRISTOPHER, DECOLLO TODD VINCENT
Format: Patent
Sprache:eng
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Zusammenfassung:Novel pyrrazole derivative compounds and their use as pharmaceutical agents, in particular their use as TGF-beta signal transduction inhibitors. The disclosed invention relates to compounds of the structure (I) wherein (I) is a four, five, or six membered saturated ring and X is C, O or S