Sünteetilised HIV geenid

Synthetic DNA molecules encoding HIV genes and modifications of HIV genes are provided. The codons of the synthetic molecules use codons preferred by the projected host cell. The synthetic molecules may be used as a polynucleotide vaccine which provides effective immunoprophylaxis against HIV infect...

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Bibliographische Detailangaben
Hauptverfasser: JOHN W. SHIVER, MARY-ELLEN M. DAVIES, HELEN C. PERRY, MARGARET A. LIU, DANIEL C. FREED
Format: Patent
Sprache:est
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Beschreibung
Zusammenfassung:Synthetic DNA molecules encoding HIV genes and modifications of HIV genes are provided. The codons of the synthetic molecules use codons preferred by the projected host cell. The synthetic molecules may be used as a polynucleotide vaccine which provides effective immunoprophylaxis against HIV infection through neutralizing antibody and cell-mediated immunity.