COMPOSICIÓN FARMACÉUTICA DE LIBERACIÓN PROLONGADA DE TRIMETAZIDINA

Composición de liberación prolongada de trimetazidina en la que la fase interna comprende trimetazidina y la capa externa comprende un retardante y un anti-aglomerante. Composition for prolonged release of trimetazidine, comprises an inner phase comprising trimetazidine and an outer layer comprising...

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Bibliographische Detailangaben
Hauptverfasser:	HERMELIN, CHRISTOPHE, PEAN, JEAN-MANUEL, GENTY, PATRICK
Format:	Patent
Sprache:	spa
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	Composición de liberación prolongada de trimetazidina en la que la fase interna comprende trimetazidina y la capa externa comprende un retardante y un anti-aglomerante. Composition for prolonged release of trimetazidine, comprises an inner phase comprising trimetazidine and an outer layer comprising a retardant and an antiagglomerant. An independent claim is included for preparing the composition comprising coating the neutral cores with trimetazidine and the binder to form minigranules, coating the minigranules with the retardant, the plasticizer and the antiagglomerant, and filling the coated minigranules into capsules, optionally in the presence of a lubricant. ACTIVITY : Antianginal; Ophthalmological; Auditory. MECHANISM OF ACTION : None given.