PYRAZOLES DERIVATIVES MODULATORS OF CALCIUM RELEASE-ACTIVATED CALCIUM CHANNEL AND METHODS FOR TREATMENT OF NON-SMALL CELL LUNG CANCER

Disclosed are novel calcium release-activated calcium (CRAC) channel inhibitors, which are compounds of general formula (I)or pharmaceutically acceptable salts thereof. Also disclosed are pharmaceutical compositions containing said compounds and methods for treating non-small cell lung cancer (NSCLC...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	MUTHUPPALANIAPPAN Meyyappan, VAKKALANKA Swaroop, Kumar, V., S, MERIKAPUDI Gayatri, Swaroop, VISWANADHA Srikant, VARANASI Kanthikiran, Vs
Format:	Patent
Sprache:	eng ; rus
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Disclosed are novel calcium release-activated calcium (CRAC) channel inhibitors, which are compounds of general formula (I)or pharmaceutically acceptable salts thereof. Also disclosed are pharmaceutical compositions containing said compounds and methods for treating non-small cell lung cancer (NSCLC) with said CRAC inhibitors. В изобретении представлены новые ингибиторы кальциевых каналов, активируемых высвобождением кальция (CRAC), представляющие собой соединения общей формулы (I)или их фармацевтически приемлемые соли. Также описаны фармацевтические композиции, содержащие указанные соединения, а также способы лечения немелкоклеточного рака легких (NSCLC) при помощи указанных ингибиторов CRAC.