PSEUDOMYCIN NATURAL PRODUCTS

1. An isolated pseudomycin of general formula wherein Y is a radical or a pharmaceutically acceptable salt, hydrate or ester thereof. 2. The pseudomycin of claim 1, comprising pseudomycin A' having the formula a pharmaceutically acceptable salt, hydrate or ester thereof. 3. The pseudomycin of claim 1, comprising pseudomycin B' having the formula a pharmaceutically acceptable salt, hydrate or ester thereof. 4. A method of inhibiting fungal activity comprising contacting a fungus with an isolated pseudomycin natural product comprising a pseudomycin A', a pseudomycin B', a mixture thereof, or a pharmaceutically acceptable salt, hydrate or ester thereof. 5. A method of reducing the symptoms of a fungal infection in a patient in need thereof comprising administering to the patient an effective amount of a composition comprising an isolated pseudomycin natural product comprising a pseudomycin A', a pseudomycin B', a mixture thereof, or a pharmaceutically acceptable salt, hydrate or ester thereof of claim 1. 6. The use of the compounds of Claim 1 in the manufacture of a pharmaceutical composition for inhibiting fungal activity. 7. The use of the compounds of Claim 1 in the manufacture of a pharmaceutical composition for inhibiting fungal activity or reducing the symptoms of a fungal infection in a patient. 8. A method of fungus inhibiting in or on a plant comprising contacting said plant with an isolated pseudomycin of claim 1 selected from the pseudomycin A' of the formula or from the pseudomycin B' of the formula or a pharmaceutically acceptable salt, hydrate or ester thereof. Данное изобретение относится к псевдомициновым природным продуктам, включая псевдомицины А' и В', способам получения таких псевдомицинов и способам использования противогрибковой активности таких псевдомицинов. ЯМР и масс-спектрометрия показывают формулу (I) для псевдомицина А'. ЯМР и масс-спектрометрия показывают формулу (II) для псевдомицина В'.