Formuleringer af en plasmakallikreinhæmmer

The present invention provides pharmaceutical dosage forms in the form of an orodispersible tablet comprising a plasma kallikrein inhibitor, mixtures for use in manufacturing processes for producing the orodispersible tablets of the invention and the uses of such orodispersible tablets. The orodispe...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: ARROYO, Ana Catalina Ferreira, SMITH, Michael David, SCHIANO, Serena, IVERSON, Matthew Scott, COOPER, John Alexander, CROADSHAW, Oliver William
Format: Patent
Sprache:dan
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Beschreibung
Zusammenfassung:The present invention provides pharmaceutical dosage forms in the form of an orodispersible tablet comprising a plasma kallikrein inhibitor, mixtures for use in manufacturing processes for producing the orodispersible tablets of the invention and the uses of such orodispersible tablets. The orodispersible tablets of the present invention are particularly suitable for patients who may struggle to swallow tablets. The present invention provides on-demand treatments of bradykinin-mediated angioedema by orally administering a plasma kallikrein inhibitor to a patient in need thereof in the form of an orodispersible tablet.