IMIDAZOLDERIVATER OG SALTE DERAF SAMT FREMGANGSMAADE OG MELLEMPRODUKTER TIL DERES FREMSTILLING

Pharmaceutical formulations comprising an imidazole (or pharmaceutically acceptable salt thereof) of formula:wherein(i) A is an aliphatic hydrocarbon residue of from 1 to 4 carbon atoms and R is a naphthyl, tetrahydronaphthyl, heterocyclyl, arylthio, arylalkylthio, aryloxy, arylalkyloxy, arylhydroxy...

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description Pharmaceutical formulations comprising an imidazole (or pharmaceutically acceptable salt thereof) of formula:wherein(i) A is an aliphatic hydrocarbon residue of from 1 to 4 carbon atoms and R is a naphthyl, tetrahydronaphthyl, heterocyclyl, arylthio, arylalkylthio, aryloxy, arylalkyloxy, arylhydroxymethylene, arylcarbonyl, arylalkylcarbonyl, alkyloxy, alkylthio or a substituted cycloalkyl or cycloalkenyl group or(ii) A is a -S02- group and R is aryl or heterocyclyl or(iii) A is a chemical bond and R is a heterocyclyl or substituted phenyl group, or(iv) A is an aliphatic hydrocarbon residue of from 1 to 3 carbon atoms and R is a halophenyl group.Some of these imidazoles and salts are novel.Methods of preparing the imidazoles are disclosed. The imidazoles and their salts are useful in the treatment or prophylaxis of thrombo-embolic conditions.
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The imidazoles and their salts are useful in the treatment or prophylaxis of thrombo-embolic conditions.</abstract><edition>3</edition><oa>free_for_read</oa></addata></record>
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subjects ACYCLIC OR CARBOCYCLIC COMPOUNDS
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title IMIDAZOLDERIVATER OG SALTE DERAF SAMT FREMGANGSMAADE OG MELLEMPRODUKTER TIL DERES FREMSTILLING
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