IMIDAZOLDERIVATER OG SALTE DERAF SAMT FREMGANGSMAADE OG MELLEMPRODUKTER TIL DERES FREMSTILLING

Pharmaceutical formulations comprising an imidazole (or pharmaceutically acceptable salt thereof) of formula:wherein(i) A is an aliphatic hydrocarbon residue of from 1 to 4 carbon atoms and R is a naphthyl, tetrahydronaphthyl, heterocyclyl, arylthio, arylalkylthio, aryloxy, arylalkyloxy, arylhydroxy...

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1. Verfasser:	THOROGOOD P B
Format:	Patent
Sprache:	dan
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Pharmaceutical formulations comprising an imidazole (or pharmaceutically acceptable salt thereof) of formula:wherein(i) A is an aliphatic hydrocarbon residue of from 1 to 4 carbon atoms and R is a naphthyl, tetrahydronaphthyl, heterocyclyl, arylthio, arylalkylthio, aryloxy, arylalkyloxy, arylhydroxymethylene, arylcarbonyl, arylalkylcarbonyl, alkyloxy, alkylthio or a substituted cycloalkyl or cycloalkenyl group or(ii) A is a -S02- group and R is aryl or heterocyclyl or(iii) A is a chemical bond and R is a heterocyclyl or substituted phenyl group, or(iv) A is an aliphatic hydrocarbon residue of from 1 to 3 carbon atoms and R is a halophenyl group.Some of these imidazoles and salts are novel.Methods of preparing the imidazoles are disclosed. The imidazoles and their salts are useful in the treatment or prophylaxis of thrombo-embolic conditions.