FREMGANGSMAADE TIL FREMSTILLING AF APOVINCAMINSYREESTERE

FREMGANGSMAADE TIL FREMSTILLING AF APOVINCAMINSYREESTERE

Apovincaminic acid esters of the general formula (I> (wherein R and R independently represent alkyl groups having from 1 to 6 carbon atoms) may be prepared by reacting a hydroxyamino-E-homo- eburnane of the general formula (II> (wherein R and R are as defined above) or an acid addition salt th...

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Hauptverfasser: CZIBULA L, FARKAS M, SZABO L, NEMES A, VISKY G, KALAUS G, KREIDL J, SZANTAY C
Format: Patent
Sprache:dan
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:Apovincaminic acid esters of the general formula (I> (wherein R and R independently represent alkyl groups having from 1 to 6 carbon atoms) may be prepared by reacting a hydroxyamino-E-homo- eburnane of the general formula (II> (wherein R and R are as defined above) or an acid addition salt thereof with an organic sulfonic acid, in an aprotic organic solvent. The compounds of the general formula (I) are useful pharmaceuticals.