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The present invention relates to compounds that are Nrf2 activators. The compounds have the structural formula I defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment o...

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Bibliographische Detailangaben
Hauptverfasser:	RAY, Nick Charles, RUSSELL, Michael Geoffrey Neil, ROUSSEL, Fabien Jean Ghislain, LUCAS, Cathy Louise, CRUMPLER, Simon Ross, YEAP, Siew Kuen, EVANS, David Gareth, MARTIN, Barrie Phillip, NOWAK, Thorsten, LE BOZEC, Lucille, SEHMI, Sanjeet Singh, CRICK, Duncan James, HYND, George, BLANEY, Emma Louise, SEWARD, Eileen Mary
Format:	Patent
Sprache:	dan
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present invention relates to compounds that are Nrf2 activators. The compounds have the structural formula I defined herein. The present invention also relates to processes for the preparation of these compounds, to pharmaceutical compositions comprising them, and to their use in the treatment of diseases or disorders associated with Nrf2 activation.