Selektive østrogenreceptornedbrydere

Selektive østrogenreceptornedbrydere

Novel selective estrogen receptor degraders (SERDs) according to the formula:pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, wherein either R1 or R2 is independently selected from Cl, F, -CF3, or -CH3, and the other is hydrogen, and methods for their use are provi...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: COHEN, Jeffrey Daniel, BASTIAN, Jolie Anne, MCMAHON, Jennifer Anne, SALL, Daniel Jon, RUBIO, Almudena
Format: Patent
Sprache:dan
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Novel selective estrogen receptor degraders (SERDs) according to the formula:pharmaceutically acceptable salts thereof, and pharmaceutical compositions thereof, wherein either R1 or R2 is independently selected from Cl, F, -CF3, or -CH3, and the other is hydrogen, and methods for their use are provided.