Biomarkøranalyse for diagnostiske multiplexdata med højt gennemløb

Flow cytometry of extracellular vesicle (EV) samples produces counts associated with channels defined by combinations of capture agents and detection agents, typically capture antibodies and detection antibodies having associated markers such as fluorophores. Sample groupings are obtained by process...

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Hauptverfasser: BERZOFSKY, Jay A, WELSH, Joshua Aden, JONES, Jennifer C
Format: Patent
Sprache:dan
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Zusammenfassung:Flow cytometry of extracellular vesicle (EV) samples produces counts associated with channels defined by combinations of capture agents and detection agents, typically capture antibodies and detection antibodies having associated markers such as fluorophores. Sample groupings are obtained by processing channel counts using principal component analysis or other techniques. Identification of a particular sample grouping permits selection of associated channels for detection of samples exhibiting characteristics of the particular sample grouping.