STABIL LYOFILISERET FORMULERING TIL HYBRID FC-FUSIONERET G-CSF

The present formulation comprises a stable lyophilized formulation, suitable for administration via a subcutaneous (SC) route, comprising Fc fused to Granulocyte Colony Stimulating Factor (G-CSF) molecules via peptide bond, stabilizer, surfactant and buffer, at pH value of the preparation that is be...

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Bibliographische Detailangaben
Hauptverfasser: PINARBASLI, Onur, Sahin, Adem, SARRACOGLU, Nagehan, Özkan, Aylin, Çorbacioglu Pala, Meltem, Öncel, Hatice, Daglikoca, Emine Duygu
Format: Patent
Sprache:dan
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Zusammenfassung:The present formulation comprises a stable lyophilized formulation, suitable for administration via a subcutaneous (SC) route, comprising Fc fused to Granulocyte Colony Stimulating Factor (G-CSF) molecules via peptide bond, stabilizer, surfactant and buffer, at pH value of the preparation that is between 3.8 and 5.2.