FARMACEUTISKE SAMMENSÆTNINGER AF 6H-PYRIDO[3,2-E][1,2,4]TRIAZOLO[1,5-C]PYRIMIDIN-5-ON- OG [1,2,4]TRIAZOLO[1,5-C]PTERIDIN-5(6H)-ON-DERIVATER SOM PDE1-INHIBITORER TIL BEHANDLING AF FOR EKSEMPEL NEUROLOGISKE LIDELSER

The present invention relates to 6-benzyl-6H-pyrido[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-5-one and 6-benzyl-[1,2,4]triazolo[1,5-c]pteridin-5(6H)-one derivatives as phosphodiesterase 1 (PDE1) inhibitors for the treatment of e.g. neurological disorders, cognitive disorders, cardiovascular disorders,...

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Bibliographische Detailangaben
Hauptverfasser:	BRANSTETTER, Bryan, PETERS, Marco, MARRONE, Tami, Jo, WEINHOUSE, Michael, I, DYCK, Brian, ALLAN, Amy, GOMEZ, Laurent
Format:	Patent
Sprache:	dan
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to 6-benzyl-6H-pyrido[3,2-e][1,2,4]triazolo[1,5-c]pyrimidin-5-one and 6-benzyl-[1,2,4]triazolo[1,5-c]pteridin-5(6H)-one derivatives as phosphodiesterase 1 (PDE1) inhibitors for the treatment of e.g. neurological disorders, cognitive disorders, cardiovascular disorders, renal disorders and atherosclerosis.