GENOMREDIGERINGSSYSTEMER OG ANVENDELSESFREMGANGSMÅDER

Compositions and methods are provided for genome editing at a target site in the genome of a filamentous fungal cell. The methods and compositions disclosed are drawn to a guide polynucleotide/Cas endonuclease system and donor polynucleotides with shorter homology arms (i.e., less than 500 bps) to a...

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Hauptverfasser: SCHMIDT, Brian F, MADRID, Susan Mampusti, BAO, Kai
Format: Patent
Sprache:dan
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Zusammenfassung:Compositions and methods are provided for genome editing at a target site in the genome of a filamentous fungal cell. The methods and compositions disclosed are drawn to a guide polynucleotide/Cas endonuclease system and donor polynucleotides with shorter homology arms (i.e., less than 500 bps) to a genomic locus of the fungal cell.