6,7-DIHYDROPYRAZOLO[1,5-A]PYRAZIN-4(5H)-ONFORBINDELSER OG DERES ANVENDELSE SOM NEGATIVE ALLOSTERISKE MODULATORER AF MGLU2-RECEPTORER
The present invention relates to novel 6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one derivatives as negative allosteric modulators (NAMs) of the metabotropic glutamate receptor subtype 2 ("mGluR2"). The invention is also directed to pharmaceutical compositions comprising such compounds, to p...
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| creator | TRABANCO-SUÁREZ, Andrés, Avelino VAN GOOL, Michiel, Luc, Maria ALONSO-DE DIEGO, Sergio-Alvar DELGADO-GONZÁLEZ, Óscar ANDRÉS-GIL, José, Ignacio |
| description | The present invention relates to novel 6,7-dihydropyrazolo[1,5-a]pyrazin-4(5H)-one derivatives as negative allosteric modulators (NAMs) of the metabotropic glutamate receptor subtype 2 ("mGluR2"). The invention is also directed to pharmaceutical compositions comprising such compounds, to processes for preparing such compounds and compositions, and to the use of such compounds and compositions for the prevention or treatment of disorders in which the mGluR2 subtype of metabotropic receptors is involved. |
| format | Patent |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | 6,7-DIHYDROPYRAZOLO[1,5-A]PYRAZIN-4(5H)-ONFORBINDELSER OG DERES ANVENDELSE SOM NEGATIVE ALLOSTERISKE MODULATORER AF MGLU2-RECEPTORER |
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