Histone demethylase inhibitors

The present disclosure relates generally to compositions and methods for treating cancer and neoplastic disease. Provided herein are substituted pyridine derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for inhibition h...

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Bibliographische Detailangaben
Hauptverfasser: WALLACE, Michael, Brennan, BOLOOR, Amogh, CHEN, Young, K
Format: Patent
Sprache:dan
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Beschreibung
Zusammenfassung:The present disclosure relates generally to compositions and methods for treating cancer and neoplastic disease. Provided herein are substituted pyridine derivative compounds and pharmaceutical compositions comprising said compounds. The subject compounds and compositions are useful for inhibition histone demethylase. Furthermore, the subject compounds and compositions are useful for the treatment of cancer, such as prostate cancer, breast cancer, bladder cancer, lung cancer and/or melanoma and the like.