REPROGRAMMERING AF T-CELLER OG HÆMATOPOIETISKE CELLER

REPROGRAMMERING AF T-CELLER OG HÆMATOPOIETISKE CELLER

Methods and compositions relating to the production of induced pluripotent stem cells (iPS cells) are disclosed. For example, induced pluripotent stem cells may be generated from CD34 + hematopoietic cells, such as human CD34 + blood progenitor cells, or T cells. Various iPS cell lines are also prov...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: RAJESH, Deepika, NUWAYSIR, Emile, BROWN, Matthew, MACK, Amanda, LEARISH, Randy, DOMINGUEZ, Elizabeth Rondon
Format: Patent
Sprache:dan
Schlagworte:
BEER
BIOCHEMISTRY
CHEMISTRY
COMPOSITIONS THEREOF
CULTURE MEDIA
ENZYMOLOGY
METALLURGY
MICROBIOLOGY
MICROORGANISMS OR ENZYMES
MUTATION OR GENETIC ENGINEERING
PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Beschreibung
Zusammenfassung:Methods and compositions relating to the production of induced pluripotent stem cells (iPS cells) are disclosed. For example, induced pluripotent stem cells may be generated from CD34 + hematopoietic cells, such as human CD34 + blood progenitor cells, or T cells. Various iPS cell lines are also provided. In certain embodiments, the invention provides novel induced pluripotent stem cells with a genome comprising genetic rearrangement of T cell receptors.