FREMGANGSMAADE TIL FREMSTILLING AF ZIDOVUDIN SAMT MELLEMPRODUKTER VED FREMGANGSMAADEN

This invention relates to a new synthetic process for the manufacture of zidovudine from the starting material D-xylose involving: i) Conversion of D-xylose to a 1-( beta -D-xylofuranosyl)thymine derivative; ii) 2 min -Deoxygenation of the thymine derivative; and iii) 3 min -Azidation of the 2 min -...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	RIDEOUT, JANET LITSTER, WILSON, JEFFREY DOUGLAS, ALMOND, MERRICK RICHARD
Format:	Patent
Sprache:	dan
Schlagworte:	CHEMISTRY DERIVATIVES THEREOF HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY NUCLEIC ACIDS NUCLEOSIDES NUCLEOTIDES ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SUGARS
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	This invention relates to a new synthetic process for the manufacture of zidovudine from the starting material D-xylose involving: i) Conversion of D-xylose to a 1-( beta -D-xylofuranosyl)thymine derivative; ii) 2 min -Deoxygenation of the thymine derivative; and iii) 3 min -Azidation of the 2 min -deoxy compound. r