Sulfonamidderivat og medicinsk anvendelse deraf

Sulfonamidderivat og medicinsk anvendelse deraf

Provided is a sulfonamide derivative represented by the following general formula (1) and having an ±4 integrin inhibitory effect with high selectivity with a low effect on ±4²1 and a high effect on ±4²7, or a pharmaceutically acceptable salt thereof (in the general formula (1), A, B, D, E, R 41 , a...

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Bibliographische Detailangaben
Hauptverfasser: SHINKAI Kenji, ARISAKA Harumi, TAKANOHASHI Toshiyuki, YAMAMOTO Takashi, UENO Hirokazu, MIYAZAWA Tomoko
Format: Patent
Sprache:dan
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:Provided is a sulfonamide derivative represented by the following general formula (1) and having an ±4 integrin inhibitory effect with high selectivity with a low effect on ±4²1 and a high effect on ±4²7, or a pharmaceutically acceptable salt thereof (in the general formula (1), A, B, D, E, R 41 , and a to h are as described in the description).