FREMGANGSMAADE TIL FREMSTILLING AF ANTIBIOTIKA AKLACINOMYCIN A OG B MED ANTICANCER-VIRKNING ELLER BLANDINGER DERAF SAMT STREPTOMYCES LAVENDOFOLIAE-STAMMEN 12/3-A

FREMGANGSMAADE TIL FREMSTILLING AF ANTIBIOTIKA AKLACINOMYCIN A OG B MED ANTICANCER-VIRKNING ELLER BLANDINGER DERAF SAMT STREPTOMYCES LAVENDOFOLIAE-STAMMEN 12/3-A

The antibiotics aclacinomycin A and B which have anticancer activity, and mixtures thereof, are obtained by cultivation of the strain 12/3-A of Streptomyces lavendofoliae under aerobic conditions in a nutrient medium which contains carbon- and nitrogen-containing compounds at a temperature of 20 - 3...

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Hauptverfasser: ESIPOV S.E, TERENTIEVA T.G, KRJUCHKOVA E.I, NAVASHIN S.M, KLJUEV N.A, EGOROV L.V, SINGAL E.M, CHERNYSHEV A.I, VESELOVA S.I, TAIG M.M, SOIFER V.S, OSTANINA L.N, IVANITSKAYA L.P, FOMINA I.P
Format: Patent
Sprache:dan
Schlagworte:
BEER
BIOCHEMISTRY
CHEMISTRY
ENZYMOLOGY
FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE
METALLURGY
MICROBIOLOGY
MUTATION OR GENETIC ENGINEERING
PROCESSES USING MICROORGANISMS
SPIRITS
VINEGAR
WINE
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Zusammenfassung:The antibiotics aclacinomycin A and B which have anticancer activity, and mixtures thereof, are obtained by cultivation of the strain 12/3-A of Streptomyces lavendofoliae under aerobic conditions in a nutrient medium which contains carbon- and nitrogen-containing compounds at a temperature of 20 - 30 DEG C and at a pH of 6 - 8.5 for 48 - 96 h.