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Disclosed is the use of the reactive components of the inverse electron-demand Diels Alder reaction for chemical masking and unmasking in vitro. This can be applied in complex chemical reactions and, particularly in the synthesis of biomolecules, e.g. on solid supports. The reactive components are a...

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Bibliographische Detailangaben
Hauptverfasser: VERSTEEGEN, Ronny Mathieu, ROSSIN, Raffaella, TEN HOEVE, Wolter, ROBILLARD, Marc Stefan
Format: Patent
Sprache:dan
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Zusammenfassung:Disclosed is the use of the reactive components of the inverse electron-demand Diels Alder reaction for chemical masking and unmasking in vitro. This can be applied in complex chemical reactions and, particularly in the synthesis of biomolecules, e.g. on solid supports. The reactive components are a dienophile, particularly a trans-cyclooctene, and a diene, particularly a tetrazine.