FREMGANGSMAADE TIL FREMSTILLING AF PYRIMIDONDERIVATER

The present invention provides compounds of formula (2):and their pharmaceutically acceptable salts which are useful as histamine H1-antagonists. In formula (2) R' is halogen or nitro; R' is C1-4 alkyl: R3 is a C1-3 alkylene group; and R4 is 3-pyridyl; N-oxo-3-pyridyl; 6-methyl-3-pyridyl;...

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description The present invention provides compounds of formula (2):and their pharmaceutically acceptable salts which are useful as histamine H1-antagonists. In formula (2) R' is halogen or nitro; R' is C1-4 alkyl: R3 is a C1-3 alkylene group; and R4 is 3-pyridyl; N-oxo-3-pyridyl; 6-methyl-3-pyridyl; N-oxo-6-methyl-3-pyridyl; 6-hydroxymethyl-3-pyridyl; 4,6-dimethyl-3-pyridyl; N-oxo-4.6-dimethyl-3-pyridyl; 6-hydroxymethyl-4-methyl-3-pyridyl; 5,6-dimethyl-3-pyridyl; N-oxo-5,6-dimethyl-3-pyridyl; 6-hydroxymethyl-5-methyl-3-pyridyl; 4-pyridyl or N-oxo-4-pyridyl.
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In formula (2) R' is halogen or nitro; R' is C1-4 alkyl: R3 is a C1-3 alkylene group; and R4 is 3-pyridyl; N-oxo-3-pyridyl; 6-methyl-3-pyridyl; N-oxo-6-methyl-3-pyridyl; 6-hydroxymethyl-3-pyridyl; 4,6-dimethyl-3-pyridyl; N-oxo-4.6-dimethyl-3-pyridyl; 6-hydroxymethyl-4-methyl-3-pyridyl; 5,6-dimethyl-3-pyridyl; N-oxo-5,6-dimethyl-3-pyridyl; 6-hydroxymethyl-5-methyl-3-pyridyl; 4-pyridyl or N-oxo-4-pyridyl.</description><edition>3</edition><language>dan</language><subject>CHEMISTRY ; COLOUR PRINTING ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; LINING MACHINES ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PERFORMING OPERATIONS ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; PRINTING ; PRINTING, DUPLICATING, MARKING, OR COPYING PROCESSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS ; STAMPS ; TRANSPORTING ; TYPEWRITERS</subject><creationdate>1982</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19821228&amp;DB=EPODOC&amp;CC=DK&amp;NR=286982A$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25543,76293</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=19821228&amp;DB=EPODOC&amp;CC=DK&amp;NR=286982A$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>SACH G S</creatorcontrib><title>FREMGANGSMAADE TIL FREMSTILLING AF PYRIMIDONDERIVATER</title><description>The present invention provides compounds of formula (2):and their pharmaceutically acceptable salts which are useful as histamine H1-antagonists. In formula (2) R' is halogen or nitro; R' is C1-4 alkyl: R3 is a C1-3 alkylene group; and R4 is 3-pyridyl; N-oxo-3-pyridyl; 6-methyl-3-pyridyl; N-oxo-6-methyl-3-pyridyl; 6-hydroxymethyl-3-pyridyl; 4,6-dimethyl-3-pyridyl; N-oxo-4.6-dimethyl-3-pyridyl; 6-hydroxymethyl-4-methyl-3-pyridyl; 5,6-dimethyl-3-pyridyl; N-oxo-5,6-dimethyl-3-pyridyl; 6-hydroxymethyl-5-methyl-3-pyridyl; 4-pyridyl or N-oxo-4-pyridyl.</description><subject>CHEMISTRY</subject><subject>COLOUR PRINTING</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>LINING MACHINES</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PERFORMING OPERATIONS</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>PRINTING</subject><subject>PRINTING, DUPLICATING, MARKING, OR COPYING PROCESSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><subject>STAMPS</subject><subject>TRANSPORTING</subject><subject>TYPEWRITERS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>1982</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZDB1C3L1dXf0cw_2dXR0cVUI8fRRAAkFAxk-nn7uCo5uCgGRQZ6-ni7-fi6uQZ5hjiGuQTwMrGmJOcWpvFCam0HOzTXE2UM3tSA_PrW4IDE5NS-1JN7F28jCzNLCyNGYoAIAKL0myw</recordid><startdate>19821228</startdate><enddate>19821228</enddate><creator>SACH G S</creator><scope>EVB</scope></search><sort><creationdate>19821228</creationdate><title>FREMGANGSMAADE TIL FREMSTILLING AF PYRIMIDONDERIVATER</title><author>SACH G S</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_DK286982A3</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>dan</language><creationdate>1982</creationdate><topic>CHEMISTRY</topic><topic>COLOUR PRINTING</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>LINING MACHINES</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PERFORMING OPERATIONS</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>PRINTING</topic><topic>PRINTING, DUPLICATING, MARKING, OR COPYING PROCESSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><topic>STAMPS</topic><topic>TRANSPORTING</topic><topic>TYPEWRITERS</topic><toplevel>online_resources</toplevel><creatorcontrib>SACH G S</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>SACH G S</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>FREMGANGSMAADE TIL FREMSTILLING AF PYRIMIDONDERIVATER</title><date>1982-12-28</date><risdate>1982</risdate><abstract>The present invention provides compounds of formula (2):and their pharmaceutically acceptable salts which are useful as histamine H1-antagonists. In formula (2) R' is halogen or nitro; R' is C1-4 alkyl: R3 is a C1-3 alkylene group; and R4 is 3-pyridyl; N-oxo-3-pyridyl; 6-methyl-3-pyridyl; N-oxo-6-methyl-3-pyridyl; 6-hydroxymethyl-3-pyridyl; 4,6-dimethyl-3-pyridyl; N-oxo-4.6-dimethyl-3-pyridyl; 6-hydroxymethyl-4-methyl-3-pyridyl; 5,6-dimethyl-3-pyridyl; N-oxo-5,6-dimethyl-3-pyridyl; 6-hydroxymethyl-5-methyl-3-pyridyl; 4-pyridyl or N-oxo-4-pyridyl.</abstract><edition>3</edition><oa>free_for_read</oa></addata></record>
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subjects CHEMISTRY
COLOUR PRINTING
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
LINING MACHINES
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PERFORMING OPERATIONS
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
PRINTING
PRINTING, DUPLICATING, MARKING, OR COPYING PROCESSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
STAMPS
TRANSPORTING
TYPEWRITERS
title FREMGANGSMAADE TIL FREMSTILLING AF PYRIMIDONDERIVATER
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