FREMGANGSMAADE TIL FREMSTILLING AF PYRIMIDONDERIVATER

The present invention provides compounds of formula (2):and their pharmaceutically acceptable salts which are useful as histamine H1-antagonists. In formula (2) R' is halogen or nitro; R' is C1-4 alkyl: R3 is a C1-3 alkylene group; and R4 is 3-pyridyl; N-oxo-3-pyridyl; 6-methyl-3-pyridyl;...

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1. Verfasser:	SACH G S
Format:	Patent
Sprache:	dan
Schlagworte:	CHEMISTRY COLOUR PRINTING HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE LINING MACHINES MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PERFORMING OPERATIONS PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PRINTING PRINTING, DUPLICATING, MARKING, OR COPYING PROCESSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS STAMPS TRANSPORTING TYPEWRITERS
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Beschreibung
Zusammenfassung:	The present invention provides compounds of formula (2):and their pharmaceutically acceptable salts which are useful as histamine H1-antagonists. In formula (2) R' is halogen or nitro; R' is C1-4 alkyl: R3 is a C1-3 alkylene group; and R4 is 3-pyridyl; N-oxo-3-pyridyl; 6-methyl-3-pyridyl; N-oxo-6-methyl-3-pyridyl; 6-hydroxymethyl-3-pyridyl; 4,6-dimethyl-3-pyridyl; N-oxo-4.6-dimethyl-3-pyridyl; 6-hydroxymethyl-4-methyl-3-pyridyl; 5,6-dimethyl-3-pyridyl; N-oxo-5,6-dimethyl-3-pyridyl; 6-hydroxymethyl-5-methyl-3-pyridyl; 4-pyridyl or N-oxo-4-pyridyl.