Substituerede pyrazol[1,5-a]pyridiner som tropomyosinreceptorkinase(TRK)-inhibitorer

Substituerede pyrazol[1,5-a]pyridiner som tropomyosinreceptorkinase(TRK)-inhibitorer

The present application relates to a series of substituted pyrazolo[1,5-a]pyridine compounds, their use as tropomyosin receptor kinase (Trk) family protein kinase inhibitors, method of making and pharmaceutical compositions comprising such compounds.

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Bibliographische Detailangaben
Hauptverfasser: PARADKAR, Vidyadhar, AHMED, Shahadat, TEHIM, Ashok, DATTATREYA, Prasanna M, SASMAL, Pradip Kumar, MAVINAHALLI, Nanjegowda Jagadeesh
Format: Patent
Sprache:dan
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present application relates to a series of substituted pyrazolo[1,5-a]pyridine compounds, their use as tropomyosin receptor kinase (Trk) family protein kinase inhibitors, method of making and pharmaceutical compositions comprising such compounds.