KEMISK FORBINDELSE, DER ER ANVENDELIG SOM MELLEMPRODUKT TIL FREMSTILLING AF EN CATECHOL-O-METHYLTRANSFERASEHÆMMER

There is disclosed a methylated intermediate of formula (I) which may be demethylated to provide an inhibitor of catechol-O-methyltransferase useful in the treatment of Parkinson's disease. Also disclosed are methods of making and using said intermediate.

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Bibliographische Detailangaben
Hauptverfasser: ESZENYI, Tibor, KISS, Laszlo Erno, KREIS, Michael, RUSSO, Domenico, SCHLUMMER, Bjoern, WAHNON, Jorge Bruno Reis, REITER, Klaus, ZIMMERMANN, Axel, LEARMONTH, David Alexander
Format: Patent
Sprache:dan
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Zusammenfassung:There is disclosed a methylated intermediate of formula (I) which may be demethylated to provide an inhibitor of catechol-O-methyltransferase useful in the treatment of Parkinson's disease. Also disclosed are methods of making and using said intermediate.