4-(3-JODPROPARGYLOXY) PYRIMIDINDERIVATER OG FREMGANGSMAADE TIL DERES FREMSTILLING

4-(3-JODPROPARGYLOXY) PYRIMIDINDERIVATER OG FREMGANGSMAADE TIL DERES FREMSTILLING

4-(3-Iodopropargyloxy) pyrimidine derivatives of the general formula wherein R1 is selected from among a halogen atom, an amino group, a C1-C4 alkylamino or a C1-C4 alkylthio group, and R2 is selected from among a hydrogen atom, a halogen atom, a C1-C4 alkyl group or a C1-C4 alkoxy group, are disclo...

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Bibliographische Detailangaben
Hauptverfasser: TURINOVA J, HESOUN D, VONDRACEK B
Format: Patent
Sprache:dan
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Zusammenfassung:4-(3-Iodopropargyloxy) pyrimidine derivatives of the general formula wherein R1 is selected from among a halogen atom, an amino group, a C1-C4 alkylamino or a C1-C4 alkylthio group, and R2 is selected from among a hydrogen atom, a halogen atom, a C1-C4 alkyl group or a C1-C4 alkoxy group, are disclosed. The described compounds are prepared by reacting a 4-halopyrimidine with propargyl alcohol and iodinating the resultant product in the 3 position of the propargyl chain.