Fremgangsmåde til fremstilling af pyripyropenderivater

Fremgangsmåde til fremstilling af pyripyropenderivater

Disclosed is a process for efficiently producing pyripyropene derivatives having acyloxy at the 1-position and 11-position and hydroxyl at the 7-position. The process comprises selectively acylating hydroxyl at the 1-position and 11-position of a compound represented by formula B1 through one to thr...

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Hauptverfasser: MINOWA, Nobuto, MITOMI, Masaaki, NAKANISHI, Nozomu, ANDO, Takashi, KURIHARA, Kenichi, GOTO, Kimihiko, WATANABE, Takashi, FUKUDA, Yoshimasa
Format: Patent
Sprache:dan
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Zusammenfassung:Disclosed is a process for efficiently producing pyripyropene derivatives having acyloxy at the 1-position and 11-position and hydroxyl at the 7-position. The process comprises selectively acylating hydroxyl at the 1-position and 11-position of a compound represented by formula B1 through one to three steps with an acylating agent in the presence or absence of a base.