Bicykliske forbindelser som alfa4beta2 nikotiniske acetylcholin-receptorligander

The present invention relates to novel bicyclic compounds of the formula (I), and their derivatives, prodrugs, tautomers, stereoisomers, polymorphs, solvates, hydrates, metabolites, N-oxides, pharmaceutically acceptable salts and compositions containing them. The present invention also relates to a...

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Hauptverfasser: VEERAMALLA, Srinivas, MOHAMMED, Abdul, Rasheed, SHINDE, Anil, Karbhari, KAMBHAMPTI, Rama, Sastri, BHYRAPUNENI, Gopinadh, AHMAD, Ishtiyaque, NIROGI, Ramakrishna, RAVELLA, Srinivasa, Rao, JAYARAJAN, Pradeep, JASTI, Venkateswarlu
Format: Patent
Sprache:dan
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Zusammenfassung:The present invention relates to novel bicyclic compounds of the formula (I), and their derivatives, prodrugs, tautomers, stereoisomers, polymorphs, solvates, hydrates, metabolites, N-oxides, pharmaceutically acceptable salts and compositions containing them. The present invention also relates to a process for the preparation of above said novel compounds, and their derivatives, prodrugs, tautomers, stereoisomers, polymorphs, solvates, hydrates, metabolites, N-oxides, pharmaceutically acceptable salts and compositions containing them. These compounds are useful in the treatment and prevention of various disorders that are related to α4 2 nicotinic receptors.