FREMGANGSMÅDER TIL NANOPARTIKELSCREENING, HVOR DER ANVENDES INSEKTER MED BLODHJERNEBARRIERE

There is provided an insect model for determining the penetration of nanoparticles through the BBB. The model is also directed to the use of insects for studying the environmental safety of nanoparticles. The particles are administered into the hemolymf of an insect having a BBB, such as the locust,...

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Bibliographische Detailangaben
Hauptverfasser:	ANDERSSON, OLGA, AADAL NIELSEN, PETER, ANDERSSON, GUNNAR
Format:	Patent
Sprache:	dan
Schlagworte:	INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING PHYSICS TESTING
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Beschreibung
Zusammenfassung:	There is provided an insect model for determining the penetration of nanoparticles through the BBB. The model is also directed to the use of insects for studying the environmental safety of nanoparticles. The particles are administered into the hemolymf of an insect having a BBB, such as the locust, and the uptake into the brain is analysed. Thus, in this model it is possible to investigate the potential up-take into the brain of nanoparticles circulating in the blood.